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Previous Volume 355:2703 December 21, 2006 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: With regard to the article by Jordan et al. (Sept. 21 issue),¹ if cancer stem cells are characterized in experimental studies by their ability to regrow a tumor when injected into an immunodeficient animal, then what is evaluated is the capability of a cancer cell to reinitiate a tumor in a normal tissue.² In such experiments, therefore, cancer stem cells behave like tumorigenic or metastatic cells. Hence, in a functional sense, the concept of the cancer stem cell might just be a restyling of the tumorigenicity concept.

Didier Wion, Ph.D.
François Berger, M.D., Ph.D.
INSERM Unité 318
. . . [Full Text of this Article]

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