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Previous Volume 355:2792-2793 December 28, 2006 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Nitric oxide, generated by nitric oxide synthase, is a key regulator of vascular integrity. This system is dysfunctional in many cardiovascular disorders, including hypertension. A fundamentally different pathway for the generation of nitric oxide was recently described in which the anions nitrate (NO₃^–) and nitrite (NO₂^–) are converted into nitric oxide and other bioactive nitrogen oxides.^1,2,3 Nitrate is abundant in our diet, and particularly high levels are found in many vegetables.³

We examined the effect of 3-day dietary supplementation with either sodium nitrate (at a dose of 0.1 mmol per kilogram of body weight per . . . [Full Text of this Article]

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Effects of Dietary Nitrate on Blood Pressure
Dejam A., Hunter C. J., Gladwin M. T., Lundberg J. O., Weitzberg E.
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N Engl J Med 2007; 356:1590, Apr 12, 2007. Correspondence

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