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Previous Volume 355:507-510 August 3, 2006 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The revolution in molecular biology has led to widespread appreciation of a principle first described by the British physician A.E. Garrod approximately 100 years ago — that "inborn errors of metabolism" teach us much about human biology in health and disease. Neonatal diabetes mellitus is a prime example of this principle.

Neonatal diabetes mellitus is rare, with a reported incidence of 1 per 500,000 newborns and an estimated incidence of 1 per 100,000 newborns (Hattersley A: personal communication). Most newborns with neonatal diabetes mellitus are born with intrauterine growth restriction (IUGR). The degree of IUGR is proportional to the degree . . . [Full Text of this Article]

Source Information

From the Department of Pediatrics, Children's Hospital, University of Pittsburgh, Pittsburgh.

This article has been cited by other articles:

• Shafi, T., Appel, L. J., Miller, E. R. III, Klag, M. J., Parekh, R. S. (2008). Changes in Serum Potassium Mediate Thiazide-Induced Diabetes. Hypertension 52: 1022-1029 [Abstract] [Full Text]  
• Babenko, A. P. (2008). A Novel ABCC8 (SUR1)-dependent Mechanism of Metabolism-Excitation Uncoupling. J. Biol. Chem. 283: 8778-8782 [Abstract] [Full Text]