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Dr. Murray McLachlan (Emergency Medicine): A 40-year-old woman was transferred to the emergency department of this hospital because of hypotension. She had been well until the early afternoon of the day of admission, when she left the physician's office where she worked and went home, saying that she did not feel well. At approximately 4:30 p.m., her husband arrived home and found her pale and groggy. She told him that she had ingested 100 sample tablets of amlodipine (10 mg, not specified as standard or sustained release) at the office at about 12:30 p.m., in a suicide attempt. Her husband
Management
Emergency Care of the Poisoned Patient
Management of Overdose of Calcium-Channel Blockers
Basic Principles
Chemical Classes of Calcium-Channel Blockers
Volume Replacement
Calcium Therapy
Circulatory Support
HyperinsulinemiaEuglycemia Therapy
Adrenergic-Receptor Stimulation
Toxin Removal
Mechanical Support
Follow-up
Final Diagnosis
Source Information
From the Department of Emergency Medicine, Massachusetts General Hospital, and the Department of Surgery, Harvard Medical School.
Related Letters:
Case 24-2006: A Woman with Hypotension after an Overdose of Amlodipine
Aggarwal C., Gupta S., Erickson C. P., Thompson T. M., Bryant S. M., Lu J. J., Harris N. S., Fagenholz P. J.
Extract |
Full Text |
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N Engl J Med 2006;
355:1936-1938, Nov 2, 2006.
Correspondence
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