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Volume 355:850-851 August 24, 2006 Number 8
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Ambulatory Blood-Pressure Monitoring

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 by Pickering, T. G.
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To the Editor: Variability of blood pressure is increasingly being recognized as having a predictive value in clinical outcomes independently of the 24-hour average measurement, as in the review article by Pickering and colleagues (June 1 issue).1 Whereas dipping patterns have been considered as a measure of blood-pressure variability, a classification system based on the phase and amplitude of the human circadian rhythm, interpreted in the light of reference values for sex and age,2 offers superior discrimination. In a six-year prospective study involving 297 patients with no history of morbid cardiovascular events who were undergoing 48-hour ambulatory blood-pressure monitoring,3,4 a . . . [Full Text of this Article]


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