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Volume 355:958-960 August 31, 2006 Number 9
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Caffeine for Apnea of Prematurity

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 by Schmidt, B.
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To the Editor: Schmidt et al. (May 18 issue)1 appear to misconstrue the effect of caffeine on growth. Figure 2 of the article identifies a difference in growth appearing at one week of age and reflecting a greater weight loss in babies treated with caffeine. The difference in weight gradually vanishes during the next three weeks, indicating greater weight gain in babies receiving caffeine.

Premature infants with very low birth weight rarely receive adequate growth calories in the first days of life. However, most of the 5 to 10 percent of birth weight they lose reflects a loss of water . . . [Full Text of this Article]




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