This Journal feature begins with a case vignette that includesa therapeutic recommendation. A discussion of the clinical problemand the mechanism of benefit of this form of therapy follows.Major clinical studies, the clinical use of this therapy, andpotential adverse effects are reviewed. Relevant formal guidelines,if they exist, are presented. The article ends with the authors'clinical recommendations.
A 58-year-old man has chest pain at 9:30 a.m.; 3 hours later,he calls for an ambulance. Paramedics arrive, provide standardtreatment, and transport him to the nearest emergency department.On his arrival at a small hospital at 1 . . . [Full Text of this Article]
The Clinical Problem
Pathophysiology and Effect of Therapy
Clinical Evidence
Clinical Use
Adverse Effects
Areas of Uncertainty
Guidelines
Recommendations
Source Information
From the Department of Internal Medicine (Cardiology Division), University of Virginia School of Medicine, Charlottesville (E.C.K.); and the Department of Internal Medicine (Cardiology Division), University of Texas Southwestern Medical Center, Dallas (L.D.H.).
Related Letters:
Primary Percutaneous Coronary Intervention
Brown D. C., Szabo S., Oikonomopoulos T., Hoffmeister H. M., Kashyap A. S., Kashyap S., Anand K. P., Keeley E. C., Hillis L. D.
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N Engl J Med 2007;
356:1588-1590, Apr 12, 2007.
Correspondence
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