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Volume 356:1071-1073 March 8, 2007 Number 10
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Treatment of Restenosis with a Paclitaxel-Coated Balloon Catheter

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 by Camenzind, E.
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 by Scheller, B.
To the Editor: We question the conclusion by Scheller and colleagues (Nov. 16 issue)1 that paclitaxel-coated balloon catheters significantly reduce the incidence of adverse outcomes in patients undergoing percutaneous coronary intervention for in-stent stenosis. First, the trial was reported to be a double-blind study, but the investigators were aware of assignments to study groups because the paclitaxel-coated balloons were a different color from the uncoated balloons. The reduction in major cardiac events in patients who received treatment with a paclitaxel-coated balloon was driven primarily by a reduction in target-lesion revascularization, a subjective end point that was based on symptoms and . . . [Full Text of this Article]




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