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Previous Volume 356:1466-1468 April 5, 2007 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This issue of the Journal contains the second report within about a year on the presence of natural killer T cells in the lungs of patients with asthma. The two reports represent an intersection of two complex entities — asthma, because its pathogenesis is genetically and environmentally heterogeneous, and natural killer T cells, because their functions and mechanisms of action remain unclear. Natural killer T cells make up a unique family of cells with immunoregulatory properties. They express an invariant T-cell receptor that recognizes glycolipids rather than peptides. Natural killer T cells are known to modulate the activity of disease-causing . . . [Full Text of this Article]

Source Information

From the Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, and the Oxford Centre for Respiratory Medicine, Churchill Hospital — both in Oxford, England.

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