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Previous Volume 356:1575-1576 April 12, 2007 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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A well-conducted, randomized, controlled trial provides a high level of evidence to guide clinical management. Although this tenet is accepted in all fields of medicine, including oncology, considerable challenges are associated with conducting randomized, controlled trials successfully in special patient populations such as the elderly. In this issue of the Journal, Keime-Guibert et al.¹ describe their multi-institutional trial of radiotherapy for newly diagnosed glioblastoma in patients 70 years of age or older.

Over a period of 4 years, Keime-Guibert and colleagues randomly assigned 85 elderly patients from 10 centers to receive radiotherapy plus supportive care or supportive care alone. The . . . [Full Text of this Article]

Source Information

From the Division of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, and the Department of Medicine, University of Toronto — both in Toronto.

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