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Previous Volume 356:1657-1665 April 19, 2007 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

A 56-year-old woman with a history of primary pulmonary hypertension and heart and lung transplantation was admitted to the hospital because of renal failure.

When the patient was approximately 43 years old, a diagnosis of primary pulmonary hypertension was made at another institution; progressive hypoxemia and polycythemia developed, and 3 years later (10 years before admission), heart and lung transplantation was performed at another hospital. The patient's symptoms improved, and oxygenation and hemoglobin levels returned to normal. Her medications included prednisone (10 mg daily), cyclosporine (225 mg twice daily), azathioprine (75 mg per day in divided doses), folate, hydralazine, furosemide, . . . [Full Text of this Article]

Differential Diagnosis

Chronic Kidney Disease in Nonrenal Solid-Organ Transplantation

Diabetic and Hypertensive Nephropathy

Glomerular Disease

Tubulointerstitial Disease

Vascular Disease

Complications of Immunosuppressive Drugs

            Calcineurin Inhibitors

            TOR Inhibitors

Clinical Diagnosis

Dr. Nelson B. Goes's Diagnosis

Pathological Discussion

Focal Segmental Glomerulosclerosis, Collapsing Variant

Glomerular Collapse as a Form of Cyclosporine Toxicity

Cyclosporine-Mediated Arteriolopathy

Anatomical Diagnoses

Source Information

From the Nephrology Division, Department of Medicine (N.B.G.), and the Department of Pathology (R.B.C.), Massachusetts General Hospital; and the Departments of Medicine (N.B.G.) and Pathology (R.B.C.), Harvard Medical School.

This article has been cited by other articles:

• Albaqumi, M., Barisoni, L. (2008). Current Views on Collapsing Glomerulopathy. J. Am. Soc. Nephrol. 19: 1276-1281 [Abstract] [Full Text]  
• Woywodt, A., Mengel, M. (2008). Reply. Nephrol Dial Transplant 23: 1781-1781 [Full Text]