FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 356:1751-1758 April 26, 2007 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text PowerPoint Slide Set Animation Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation

This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

During an evaluation by his internist, a 48-year-old man reports that his wife tells him that he snores loudly. Further questioning reveals that he has been falling asleep whenever sedentary. His physical examination is notable for truncal obesity (body-mass . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, New York.

Address reprint requests to Dr. Basner at the Division of Pulmonary, Allergy, and Critical Care, Columbia University College of Physicians and Surgeons, 630 W. 168th St., VC-12206, New York, NY 10032, or at rcb42@columbia.edu.

This article has been cited by other articles:

• Baranchuk, A., Healey, J. S., Simpson, C. S., Redfearn, D. P., Morillo, C. A., Connolly, S. J., Fitzpatrick, M. (2009). Atrial overdrive pacing in sleep apnoea: a meta-analysis. Europace 11: 1037-1040 [Abstract] [Full Text]  
• Lederer, D. J., Jelic, S., Basner, R. C., Ishizaka, A., Bhattacharya, J. (2009). Circulating KL-6, a biomarker of lung injury, in obstructive sleep apnoea. Eur Respir J 33: 793-796 [Abstract] [Full Text]  
• Kuhlmann, U., Bormann, F. G., Becker, H. F. (2009). Obstructive sleep apnoea: clinical signs, diagnosis and treatment. Nephrol Dial Transplant 24: 8-14 [Full Text]  
• Somers, V. K., White, D. P., Amin, R., Abraham, W. T., Costa, F., Culebras, A., Daniels, S., Floras, J. S., Hunt, C. E., Olson, L. J., Pickering, T. G., Russell, R., Woo, M., Young, T. (2008). Sleep Apnea and Cardiovascular Disease: An American Heart Association/American College of Cardiology Foundation Scientific Statement From the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing In Collaboration With the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health). Circulation 118: 1080-1111 [Full Text]  
• Somers, V. K., White, D. P., Amin, R., Abraham, W. T., Costa, F., Culebras, A., Daniels, S., Floras, J. S., Hunt, C. E., Olson, L. J., Pickering, T. G., Russell, R., Woo, M., Young, T. (2008). Sleep Apnea and Cardiovascular Disease: An American Heart Association/American College of Cardiology Foundation Scientific Statement From the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing In Collaboration With the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health). J Am Coll Cardiol 52: 686-717 [Full Text]  
• Jelic, S., Padeletti, M., Kawut, S. M., Higgins, C., Canfield, S. M., Onat, D., Colombo, P. C., Basner, R. C., Factor, P., LeJemtel, T. H. (2008). Inflammation, Oxidative Stress, and Repair Capacity of the Vascular Endothelium in Obstructive Sleep Apnea. Circulation 117: 2270-2278 [Abstract] [Full Text]