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Previous Volume 356:1760-1769 April 26, 2007 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

A 46-year-old woman came to the Center for Cancer Risk Analysis at the Cancer Center of this hospital because of recent diagnoses of endometrial, ovarian, and colonic cancers.

Fifteen weeks earlier, a routine Papanicolaou smear showed an atypical glandular cell, and she was referred to a gynecologist at this hospital. Fifteen years earlier, the patient had had abnormal findings on a Pap smear performed elsewhere; the uterine cervix was treated with cryotherapy. Over the next 14 years, repeated Papanicolaou smears were normal. She had had four early miscarriages at 6 to 8 weeks' gestation. Her menses were normal and regular. . . . [Full Text of this Article]

Differential Diagnosis

Dr. Michael V. Seiden's Diagnosis

Pathological Discussion

Discussion of Management

Recommendations for a Patient with HNPCC

Recommendations for Family Members of Patients with HNPCC

Anatomical Diagnosis

Source Information

From the Department of Medicine (M.V.S.), the Center for Cancer Risk Analysis (D.P.), the Department of Radiology (M.J.O.), and the Department of Pathology (E.O.), Massachusetts General Hospital; and the Departments of Medicine (M.V.S.), Radiology (M.J.O.), and Pathology (E.O.), Harvard Medical School.

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