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Correspondence
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Volume 356:1999-2001 May 10, 2007 Number 19
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Treatment of Infertility in the Polycystic Ovary Syndrome

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 by Legro, R. S.
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To the Editor: In their report on the treatment of infertility in women with the polycystic ovary syndrome, Legro et al. (Feb. 8 issue)1 do not mention lifestyle interventions, although a significant proportion of the women in their study were obese. Many studies have shown that weight reduction normalizes ovulation, improves hyperandrogenism, and ultimately increases rates of conception among women with the polycystic ovary syndrome.2 In fact, ovulation rates similar to those achieved in the two recent trials with metformin1,3 have been previously reported in association with lifestyle interventions.4

In addition to infertility in anovulatory women, the polycystic ovary syndrome . . . [Full Text of this Article]




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