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Volume 356:188-189 January 11, 2007 Number 2
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MODS Assay for the Diagnosis of TB

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 by Moore, D. A.J.
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To the Editor: In their article on the use of microscopic-observation drug-susceptibility (MODS) culture for the diagnosis and direct detection of multidrug-resistant tuberculosis, Moore et al. (Oct. 12 issue)1 state that MODS culture offers faster and more sensitive results than existing gold-standard methods. This study is one of the few performed in a target population with a rather simple and inexpensive method that seems to be appropriate for countries with limited resources.

However, we would like to stress that there are other options that have recently been described2 and are currently under evaluation. As compared with MODS culture, the nitrate . . . [Full Text of this Article]


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