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Previous Volume 356:2505-2513 June 14, 2007 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

An otherwise healthy 53-year-old woman is seen for routine care after completing treatment several months earlier for stage II estrogen-receptor–positive, HER2-positive breast cancer. The treatment consisted of lumpectomy, irradiation, adjuvant chemotherapy (doxorubicin and cyclophosphamide followed by paclitaxel), and trastuzumab. Her only current medication is an aromatase inhibitor. She is amenorrheic. She reports fatigue, hot flashes, arthralgias, and sexual difficulties and is concerned . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Referral for Genetic Counseling

Screening for Recurrence

            Metastases

            Local–Regional Recurrence

Screening for New Primary Cancers

            Breast Cancer

            Other Cancers

Common Symptoms Associated with Anticancer Treatments

            Hot Flashes

            Sexual Dysfunction

            Cognitive Dysfunction

            Miscellaneous Symptoms

Long-Term Risks of Breast Cancer Treatment

            Osteoporosis

            Cardiovascular Disease

            Venous Thromboembolism

Guidelines

Areas of Uncertainty

Conclusions and Recommendations

Source Information

From the University of Michigan Comprehensive Cancer Center, Ann Arbor.

Address reprint requests to Dr. Hayes at the University of Michigan Comprehensive Cancer Center, 6312 Cancer Center, 1500 E. Medical Center Dr., Ann Arbor, MI 48109, or at hayesdf@umich.edu.

Related Letters:

Follow-up of Patients with Early Breast Cancer
Sakemi H., Butsch W. S., Munoz A. J., Heimburger D. C., Hayes D. F.
Extract | Full Text | PDF  
N Engl J Med 2007; 357:1052-1053, Sep 6, 2007. Correspondence

This article has been cited by other articles:

• Ganz, P. A., Hahn, E. E. (2008). Implementing a Survivorship Care Plan for Patients With Breast Cancer. JCO 26: 759-767 [Abstract] [Full Text]  
• Sakemi, H., Butsch, W. S., Munoz, A. J., Heimburger, D. C., Hayes, D. F. (2007). Follow-up of Patients with Early Breast Cancer. NEJM 357: 1052-1053 [Full Text]