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Case Records of the Massachusetts General Hospital
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Volume 356:2515-2520 June 14, 2007 Number 24
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Case 18-2007 — A 54-Year-Old Man with Early-Stage Prostate Cancer
Donald S. Kaufman, M.D., W. Scott McDougal, M.D., Anthony L. Zietman, M.D., and Robert H. Young, M.D.

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Presentation of Case

A 54-year-old man was seen in consultation at the Multidisciplinary Genitourinary Clinic of the Cancer Center of this hospital because of a recent diagnosis of prostate cancer.

Approximately 3 years earlier, the serum prostate-specific antigen (PSA) level obtained during an annual physical examination was 5.2 ng per milliliter. One month later, transrectal ultrasonography-guided biopsy of the prostate was performed; pathological examination showed no evidence of carcinoma. Repeated PSA testing was performed on multiple occasions thereafter (Table 1). Fourteen months before the consultation, examination of another ultrasonography-guided biopsy specimen of the prostate revealed no evidence of carcinoma.

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Table 1. Serum Levels . . . [Full Text of this Article]

 
Discussion of Management

Pathological Discussion

Observation

Selection of Potentially Curative Therapy

Surgery

Radiation

Anatomical Diagnosis


Source Information

From the Departments of Hematology–Oncology (D.S.K.), Urology (W.S.M.), Radiation Oncology (A.L.Z.), and Pathology (R.H.Y.), Massachusetts General Hospital; and the Departments of Medicine (D.S.K.), Urology (W.S.M.), Radiation Oncology (A.L.Z.), and Pathology (R.H.Y.), Harvard Medical School.




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