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Volume 356:2746-2748 June 28, 2007 Number 26
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Treatment of Kawasaki Disease

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 by Burns, J. C.
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 by Newburger, J. W.
To the Editor: In their trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease, Newburger et al. (Feb. 15 issue)1 report that, as compared with placebo, a single pulsed dose of corticosteroid resulted in a shorter initial period of hospitalization but that the total numbers of days of fever and hospitalization, the rates of retreatment, and the coronary-artery outcomes did not differ significantly between the two groups. The use of a single-dose regimen without tapering most likely contributed to their results. A single application of a corticosteroid, even at a high dose, may have a strong but only . . . [Full Text of this Article]




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