The efficient and effective repair of damaged tissue is fundamentalto human survival. Wound repair has therefore challenged generationsof health care providers, and various strategies have been usedto accelerate and perfect the healing process. One such strategyhas involved the application of an exogenous electrical stimulusto chronic wounds with the aim of instigating electrotaxis (alsocalled galvanotaxis). Electrotaxis — the movement of diversecell types in response to electric gradients — has beenimplicated in the migration of cells to endogenous electricgradients generated in wounded tissue. Even though endogenouselectric fields were first identified more than . . . [Full Text of this Article]
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From the Departments of Pediatrics and Pharmacology, University of Wisconsin Medical School, Madison (A.H.); and the Department of Cell Biology, University of Virginia School of Medicine, Charlottesville (A.R.H.).
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