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Previous Volume 356:497-502 February 1, 2007 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the authors' clinical recommendations.

A 52-year-old man with an 8-year history of type 2 diabetes mellitus visits his primary care provider for advice. His glucometer readings at home have been high despite treatment with a sulfonylurea, a thiazolidinedione, and metformin at maximal doses. . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston.

Address reprint requests to Dr. McMahon at the Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, 221 Longwood Ave., RFB-2, Boston, MA 02115, or at gmcmahon@partners.org.

Related Letters:

Inhaled Insulin for Diabetes Mellitus
von Kriegstein E., von Kriegstein K., Guevara C. A., Gross J. L., Henkin R. I., McMahon G. T., Arky R. A.
Extract | Full Text | PDF  
N Engl J Med 2007; 356:2106-2108, May 17, 2007. Correspondence

This article has been cited by other articles:

• Huang, E. S., Brown, S. E.S., Ewigman, B. G., Foley, E. C., Meltzer, D. O. (2007). Patient Perceptions of Quality of Life With Diabetes-Related Complications and Treatments. Diabetes Care 30: 2478-2483 [Abstract] [Full Text]  
• von Kriegstein, E., von Kriegstein, K., Guevara, C. A., Gross, J. L., Henkin, R. I., McMahon, G. T., Arky, R. A. (2007). Inhaled Insulin for Diabetes Mellitus. NEJM 356: 2106-2108 [Full Text]