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A correction has been published: N Engl J Med 2007;356(18):1900.

Clinical Problem-Solving
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Volume 356:504-509 February 1, 2007 Number 5
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Anchors Away
Carolyn S. Calfee, M.D., Sanjiv J. Shah, M.D., Paul J. Wolters, M.D., Sanjay Saint, M.D., M.P.H., and Talmadge E. King, Jr., M.D.

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In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader (regular type). The authors' commentary follows.

A 50-year-old Asian woman presented with a papulonodular, erythematous rash on her legs below the knees. The skin lesions were nontender and nonpruritic and were accompanied by paresthesias. She had no fever, arthralgias, or other systemic symptoms.

The papulonodular rash on the legs coupled with paresthesias raises the possibility of a diagnosis of erythema nodosum. Erythema nodosum can develop as a delayed . . . [Full Text of this Article]

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From the Department of Medicine (C.S.C., S.J.S., P.J.W., T.E.K.) and Division of Pulmonary and Critical Care Medicine (C.S.C., P.J.W., T.E.K.), University of California, San Francisco; and the Department of Medicine, San Francisco General Hospital (T.E.K.) — both in San Francisco; and the Veterans Affairs Health Services Research and Development Center of Excellence (S.S.) and the Department of Internal Medicine, University of Michigan Medical School (S.S.) — both in Ann Arbor.

Address reprint requests to Dr. Calfee at the University of California, San Francisco, Pulmonary and Critical Care Division, 505 Parnassus Ave., San Francisco, CA 94143-0130, or at carolyn.calfee@ucsf.edu.


Related Letters:

Anchors Away
Morgan R. K., Berman J. S., Allan R. W., Calfee C. S., Shah S. J., King T. E. Jr.
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N Engl J Med 2007; 356:1892-1893, May 3, 2007. Correspondence

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