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Volume 356:521-522 February 1, 2007 Number 5
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Rituximab for Pemphigus Vulgaris

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 by Ahmed, A. R.
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To the Editor: Ahmed et al. (Oct. 26 issue)1 report a resolution of pemphigus in 9 of 11 patients with refractory disease treated with a combination of 10 infusions of rituximab and 6 of intravenous immune globulin. On the basis of our experience with more than 20 patients with severe pemphigus who were treated with only one cycle of four infusions of rituximab,2 we confirm that rituximab has a dramatic effect: more than 90% of our patients had a complete remission, which was maintained after a 24-month follow-up period in two thirds of the patients. We did not treat the . . . [Full Text of this Article]




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