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FOCUS ON RESEARCH Previous Volume 356:659-661 February 15, 2007 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Perspective Perspective by Newburger, J. W. Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Newburger, J. W. PubMed Citation

Two generations of clinicians and researchers have been stumped by the riddle of Kawasaki disease. How can an illness look like an infectious disease but not have a recoverable agent; look like an immune-mediated vasculitis but not be easily treated with corticosteroids; and look like a benign, self-limited illness but be the leading cause of acquired heart disease in children? The answers to the riddle continue to elude us.

Kawasaki disease affects children of all ethnic backgrounds throughout the world, although susceptibility is shaped by genetic influences. Japanese children have the highest incidence of the disease, with an attack rate . . . [Full Text of this Article]

Source Information

Dr. Burns is a professor in and chief of the Division of Pediatric Allergy, Immunology, and Rheumatology at the University of California, San Diego, School of Medicine, La Jolla.

Related Letters:

Treatment of Kawasaki Disease
Inoue Y., Kobayashi T., Morikawa A., Taddio A., Rosé C. D., Greil G. F., Manning W. J., Newburger J. W., Sleeper L. A., Burns J. C.
Extract | Full Text | PDF  
N Engl J Med 2007; 356:2746-2748, Jun 28, 2007. Correspondence

This article has been cited by other articles:

• Inoue, Y., Kobayashi, T., Morikawa, A., Taddio, A., Rose, C. D., Greil, G. F., Manning, W. J., Newburger, J. W., Sleeper, L. A., Burns, J. C. (2007). Treatment of Kawasaki Disease. NEJM 356: 2746-2748 [Full Text]  
• (2007). JournalWatch. Arch. Dis. Child. 92: 557-558 [Full Text]  
• (2007). Do Corticosteroids Improve Outcome in Kawasaki Disease?. Journal Watch Dermatology 2007: 1-1 [Full Text]  
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