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Previous Volume 356:731-733 February 15, 2007 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The sequence of the four nucleotides of the genetic code is like an indelible ink that, with rare exceptions, is faithfully transcribed from cell to cell and from generation to generation. But on top of this code lies another one, literally "epigenetic," which is represented by methyl groups added to the DNA base cytosine, as well as covalent changes in histone proteins around which the DNA is coiled. This epigenetic information is more like a code written in pencil in the margins around the DNA. Although the genome largely distinguishes one person from another, the epigenome, or epigenetic information, distinguishes . . . [Full Text of this Article]

Source Information

From the Center for Reproductive Medicine and Infertility, Weill Medical College of Cornell University, New York (R.G.G.); and the Departments of Medicine, Molecular Biology and Genetics, and Oncology, Johns Hopkins University School of Medicine, Baltimore (A.P.F.).

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