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Previous Volume 356:743-747 February 15, 2007 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The survival data from the International Early Lung Cancer Action Program (I-ELCAP) study of computed tomographic (CT) screening for lung cancer, as reported by Henschke et al. (Oct. 26 issue), are misleading.¹ These estimates of survival are potentially confounded by lead-time and overdiagnosis biases of unknown magnitude and therefore defy meaningful interpretation. Although the authors claim to report 10-year lung-cancer–specific survival rates, the median follow-up was only 40 months, and less than 20% of the subjects were observed for more than 5 years. This time horizon is probably not sufficient to assess the behavior of screening-detected lung . . . [Full Text of this Article]

This article has been cited by other articles:

• Henschke, C. I., Yankelevitz, D. F. (2008). In Reply. The Oncologist 13: 610-612 [Full Text]  
• Henschke, C. I. (2008). Reply to the Letters to the Editor from Bach and Silvestri. Clin. Cancer Res. 14: 2511-2511 [Full Text]  
• Ravenel, J. G., Costello, P., Silvestri, G. A. (2008). Screening for Lung Cancer. Am. J. Roentgenol. 190: 755-761 [Abstract] [Full Text]  
• Henschke, C. I., for the International Early Lung Cancer Action Pro, (2007). Survival of Patients with Clinical Stage I Lung Cancer Diagnosed by Computed Tomography Screening for Lung Cancer. Clin. Cancer Res. 13: 4949-4950 [Full Text]