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Previous Volume 356:820-829 February 22, 2007 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 36-year-old man with a 20-year history of type 1 diabetes mellitus, background retinopathy, peripheral sensory neuropathy, and nephropathy presents with a history of several months of nausea and vomiting of undigested food and bile, during which time he lost 4 kg. On physical examination (performed 1 hour after the patient has eaten), his blood pressure is 130/80 mm Hg while he . . . [Full Text of this Article]

The Clinical Problem

Normal Gastric Emptying

Impaired Gastric Emptying in Patients with Diabetes

Strategies and Evidence

Diagnosis

Diagnostic Testing

Management

            Exacerbating Factors

            Pharmacologic Therapy

            Prokinetic Agents

            Other Agents

            Nutritional Support

            Nonpharmacologic Therapy

            Endoscopic Injection of Botulinum Toxin

            Gastric Electrical Stimulation

            Surgery

Areas of Uncertainty

Guidelines

Summary and Recommendations

Source Information

From Clinical Enteric Neuroscience Translational and Epidemiologic Research, Mayo Clinic College of Medicine, Rochester, MN.

Address reprint requests to Dr. Camilleri at the Mayo Clinic, Miles and Shirley Fiterman Center for Digestive Diseases, Charlton 8-110, 200 First St. SW, Rochester, MN 55905, or at camilleri.michael@mayo.edu.

Related Letters:

Diabetic Gastroparesis
Heine R. J., Brodows R., Maderazo E. G., Tarsy D., Camilleri M.
Extract | Full Text | PDF  
N Engl J Med 2007; 357:418-420, Jul 26, 2007. Correspondence

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