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An afebrile 8-year-old Ethiopian girl presented with a limp. Two years earlier, she had had mild trauma followed by "bone infection" and had received short courses of oral antibiotics. Examination revealed a small, pus-secreting wound on the anterior aspect of her left thigh. Her blood count was normal, but her erythrocyte sedimentation rate was 48 mm in the first hour. A radiograph of both legs (Panel A) and an axial computed tomographic scan (Panel B) with reformatting in the sagittal plane (Panel C) showed severe deformity of the left femur, proximal small lytic lesions, destruction and condensation throughout with sequestration . . . [Full Text of this Article] |