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A 26-year-old man with a 6-month history of type 1 diabetes mellitus presented with weight loss and poor glycemic control. Physical examination revealed no xanthomas; all vessels in the posterior pole and peripheral area of each eye had a creamy appearance (Panels A and B). The patient had no problems with his vision. Laboratory studies showed a fasting blood glucose level of 261 mg per deciliter (14.5 mmol per liter; normal range, 60 to 120 mg per deciliter [3.3 to 6.7 mmol per liter]), a total serum cholesterol level of 1086 mg per deciliter (28.1 mmol per liter; normal range, . . . [Full Text of this Article] |