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Correspondence
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Volume 357:1252-1254 September 20, 2007 Number 12
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Estrogen Therapy and Coronary-Artery Calcification

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 by Mendelsohn, M. E.
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 by Manson, J. E.
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To the Editor: In their article on the Women's Health Initiative Coronary-Artery Calcium Study (WHI-CACS), Manson et al. (June 21 issue)1 provide insight into another mechanism by which estrogen therapy reduces coronary heart disease (CHD) in women who have undergone hysterectomy and who initiate such therapy close to menopause.2 The authors' findings further support the hypothesis that early initiation of such therapy has a beneficial effect.3

For women under the age of 60 years, scientific evidence indicates that estrogen therapy is as efficacious in reducing CHD as are other primary prevention therapies, such as lipid-lowering drugs and aspirin, and is . . . [Full Text of this Article]




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