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Clinical Implications of Basic Research
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Volume 357:1345-1346 September 27, 2007 Number 13
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Viral Infections and Nonspecific Protection — Good or Bad?
Emil R. Unanue, M.D.

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Viruses, like many microbes, have complex and diverse relationships with the immune system. We need to kill or control viruses to survive as a species, but under special circumstances, we could make use of them to obtain a level of protection against unrelated microbes, as was recently described by Barton and colleagues.1

The immune system is traditionally seen as a unique and highly specific system for recognition of foreign proteins, lipids, and carbohydrates. Antibody responses are exquisitely specific. In medicine, we take advantage of this high degree of specificity when we use monoclonal antibodies to treat autoimmune disorders and cancers. . . . [Full Text of this Article]


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From the Department of Pathology and Immunology, Washington University School of Medicine, St. Louis.




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