FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 357:1351-1352 September 27, 2007 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article PubMed Citation

To the Editor: In their letter to the editor, Gillessen et al. (May 31 issue)¹ report that sunitinib therapy induced macrocytosis related to cobalamin deficiency. We have made a similar observation.

Between October 2005 and March 2007, a total of 40 patients with metastatic renal-cell carcinoma (80% of whom were men; mean age, 59 years) who were receiving 50 mg of sunitinib daily were retrospectively studied for red-cell abnormalities. All patients had an increased mean corpuscular volume, and in 10 patients, the mean corpuscular volume was 105 µm³ (range, 100 to 124) (Figure 1). Five of the 10 . . . [Full Text of this Article]

Related Letters:

Macrocytosis and Cobalamin Deficiency in Patients Treated with Sunitinib
Gillessen S., Graf L., Korte W., Cerny T.
Extract | Full Text | PDF  
N Engl J Med 2007; 356:2330-2331, May 31, 2007. Correspondence

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.