Although cognitive deficits are the clinical hallmark of dementiasyndromes, noncognitive symptoms are common and can dominatethe disease course. These include a range of neuropsychiatricsymptoms, such as agitation, delusions, hallucinations, repetitivevocalizations, and wandering. Neuropsychiatric symptoms developin as many as 60% of community-dwelling patients with dementia1and in more than 80% of patients living in nursing homes. Thesesymptoms are associated with greater morbidity, higher costsof care, and reduced quality of life for the patient as wellas increased burden and depression for the caregiver. Indeed,neuropsychiatric symptoms are a primary predictor of nursinghome placement.2. . . [Full Text of this Article]
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From the Department of Psychiatry, Neurology, and Epidemiology, University of California, San Francisco.