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Volume 357:1575-1577 October 18, 2007 Number 16
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Satisfaction Guaranteed — "Payment by Results" for Biologic Agents
Alan M. Garber, M.D., Ph.D., and Mark B. McClellan, M.D., Ph.D.

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As increasing numbers of promising but expensive biologic agents are introduced for use as medical treatments, drug pricing has become a high-profile issue. Earlier this year, pricing practices took a new turn in Britain, when the National Institute for Health and Clinical Excellence (NICE), the evaluative agency that applies cost-effectiveness analysis in making recommendations concerning drug coverage, declined to support coverage of the proteasome inhibitor bortezomib (Velcade) by the British National Health Service (NHS) for the treatment of multiple myeloma. It concluded that the price was too high relative to NICE's estimates of its average benefits for the population to . . . [Full Text of this Article]


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Dr. Garber is the associate director of the Center for Health Care Evaluation and a staff physician at the Veterans Affairs Palo Alto Health Care System — both in Palo Alto, CA; and a professor of medicine, economics, and health research and policy and director of the Center for Health Policy at Stanford University, Stanford, CA. Dr. McClellan is a senior fellow and director of the Engelberg Center for Health Care Reform at the Brookings Institution and a visiting scholar at the American Enterprise Institute — both in Washington, DC.


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