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Case Records of the Massachusetts General Hospital
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Volume 357:1745-1754 October 25, 2007 Number 17
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Case 33-2007 — A 49-Year-Old HIV-Positive Man with Anemia
Eyal C. Attar, M.D., Suzanne L. Aquino, M.D., and Robert P. Hasserjian, M.D.

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Presentation of Case

A 49-year-old man infected with the human immunodeficiency virus (HIV) was seen in the hematology clinic at this hospital for evaluation of anemia.

Five weeks earlier (1 week before a routine follow-up visit with his infectious-disease specialist), laboratory testing showed anemia (Table 1). Treatment with iron and multiple vitamins was initiated, and the patient was referred for hematologic evaluation.

View this table:



 
Table 1. Results of Laboratory Tests.

 
HIV infection had been diagnosed approximately 20 years earlier, and he was followed by an infectious-disease specialist at this hospital. Eleven months earlier, the patient had discontinued antiretroviral therapy because of lipoatrophy, hyperlipidemia, and "pill . . . [Full Text of this Article]

Differential Diagnosis

Blood Loss or Hemolysis

Deficiencies of Red-Cell Production

            HIV Infection

            Pure Red-Cell Aplasia

Pathological Discussion

Dr. Eyal C. Attar's Diagnosis

Pathological Discussion

Discussion of Management

Anatomical Diagnosis


Source Information

From the Hematology–Oncology Unit (E.C.A.) and the Departments of Radiology (S.L.A.) and Pathology (R.P.H.), Massachusetts General Hospital; and the Departments of Medicine (E.C.A.), Radiology (S.L.A.), and Pathology (R.P.H.), Harvard Medical School.




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