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Previous Volume 357:1946-1955 November 8, 2007 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In 1967, Northway et al. first described a new chronic respiratory disease, bronchopulmonary dysplasia, that developed in premature infants exposed to mechanical ventilation and oxygen supplementation.¹ Two decades later, the same authors found that clinically significant respiratory symptoms and functional abnormalities persisted into adolescence and early adulthood in a cohort of survivors of bronchopulmonary dysplasia,² suggesting that lung injuries early in life may have lifelong consequences. Bronchopulmonary dysplasia is now the most common chronic lung disease of infancy in the United States.

Today, newborns consistently survive at gestational ages of 23 to 26 weeks — 8 to 10 weeks younger . . . [Full Text of this Article]

Characteristics of Bronchopulmonary Dysplasia

Pathogenesis

Epidemiology

Clinical and Functional Course of Chronic Lung Disease with Age

Symptoms

Pulmonary Function

Old versus New Bronchopulmonary Dysplasia

Asthmalike Signs and Symptoms

Treatment

Natural History of Airflow Obstruction

Conclusions and Future Directions

Source Information

From the Department of Pediatrics, Unit of Respiratory Medicine and Allergy, Unit of Neonatal Intensive Care, University of Padua, School of Medicine, Padua, Italy.

Address reprint requests to Dr. Baraldi at the Department of Pediatrics, Via Giustiniani 3, 35128 Padua, Italy, or at baraldi@pediatria.unipd.it.

Related Letters:

Chronic Lung Disease after Premature Birth
Cutz E., Chiasson D., Kiren V., Barbi E., Ventura A., Filippone M., Baraldi E.
Extract | Full Text | PDF  
N Engl J Med 2008; 358:743-746, Feb 14, 2008. Correspondence

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• Eichenwald, E. C., Stark, A. R. (2008). Management and Outcomes of Very Low Birth Weight. NEJM 358: 1700-1711 [Full Text]  
• Bush, A. (2008). Update in Pediatric Lung Disease 2007. Am. J. Respir. Crit. Care Med. 177: 686-695 [Full Text]  
• Cutz, E., Chiasson, D., Kiren, V., Barbi, E., Ventura, A., Filippone, M., Baraldi, E. (2008). Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease.. NEJM 358: 743-743 [Full Text]