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Volume 357:1996-1999 November 15, 2007 Number 20
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Closing the Affordability Gap for Drugs in Low-Income Countries
Robert Steinbrook, M.D.

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The cost of treating human immunodeficiency virus (HIV) infection is decreasing. Nonetheless, tenofovir–emtricitabine–efavirenz, the standard first-line treatment in North America and Europe, is prescribed rarely in low- and middle-income countries. The lowest annual cost for a generic formulation of this regimen is still hundreds of dollars more than the $100 annual cost of generic stavudine–lamivudine–nevirapine, an effective but less safe alternative that has been largely abandoned in Western countries (see Figure 1).1

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Figure 1. Annual Cost of Three First-Line Treatment Regimens for HIV Infection.

Panel A shows the annual price per patient of an older treatment — 30 mg of stavudine, . . . [Full Text of this Article]

 

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Dr. Steinbrook (rsteinbrook@attglobal.net) is a national correspondent for the Journal.


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