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Editorial
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Volume 357:2082-2084 November 15, 2007 Number 20
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Exoskeletons and Exhalation
Burton F. Dickey, M.D.

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-Related Article
 by Chupp, G. L.
-PubMed Citation
Chitin — the second-most abundant biologic polymer, after cellulose — is a tough, cross-linked polysaccharide (see Figure 1) found in the exoskeleton of insects and crustaceans, the cell wall of fungi, and the pharynx, microfilarial sheath, and egg of parasitic worms (helminths). The presence of chitin in so many organisms that can function as pathogens toward plants and higher animals makes it an attractive target for host recognition and enzymatic attack. Indeed, plants are well known to express chitinases in response to the presence of chitin-containing pathogens. More recently, chitinases and chitinase-like proteins have been identified in the genomes . . . [Full Text of this Article]


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From the Department of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston.


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