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Editorial
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Volume 357:2084-2086 November 15, 2007 Number 20
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Anabolic Therapy in Glucocorticoid-Induced Osteoporosis
Philip N. Sambrook, M.D.

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 by Saag, K. G.
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Glucocorticoids are widely used because of their important and efficacious immunosuppressive and antiinflammatory properties. However, glucocorticoid-induced osteoporosis, a major adverse event, is a common clinical problem. The risk of osteoporosis with glucocorticoid therapy remains unclear, but the disease has been reported to occur in up to 50% of patients who require long-term therapy. Fractures can occur rapidly, with a predilection for sites that are rich in trabecular bone, such as the spine and ribs.

There are few prospective epidemiologic data regarding fractures and their association with glucocorticoid-induced bone loss, but a large, retrospective cohort study of patients receiving glucocorticoids who . . . [Full Text of this Article]


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From the Kolling Institute, University of Sydney, Sydney.


Related Letters:

Teriparatide or Alendronate in Glucocorticoid-Induced Osteoporosis
Rossi C. M., Di Comite G., Babb R. R., Nori U. S., Agarwal A. K., Rovin B. H., Saag K. G., Shane E., Marcus R.
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N Engl J Med 2008; 358:1302-1304, Mar 20, 2008. Correspondence

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