FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 357:2630-2632 December 20, 2007 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation

Although most human cytomegalovirus (CMV) infections are asymptomatic, CMV is a significant pathogen in immunosuppressed patients such as patients with AIDS and those who receive immunosuppressive therapy after solid-organ or bone marrow transplantation. Moreover, CMV infection is a leading cause of birth defects and has been implicated in the acceleration of long-term vascular diseases such as atherosclerosis. Like infection with other herpesviruses, a primary CMV infection is followed by a lifelong persistent or latent state of the virus in the host. The key to the latent state is that infected cells avoid immune recognition and remain healthy during the production . . . [Full Text of this Article]

Source Information

From the Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton.

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.