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A 38-year-old, right-handed man was seen in the neuromuscular unit of this hospital because of weakness of the hands. He first noted shaking of his hands, the right more than the left, 8 months earlier, when he had an upper respiratory infection. The symptoms improved spontaneously, and 1 month later, he was able to play the piano. After another 3 to 4 months, he noted cramping of his right hand and decreased endurance, such that this hand would be fatigued without obvious weakness. The cramps took the form of wrist and metacarpophalangeal flexion and were relieved by shaking the hand.
Differential Diagnosis
Rheumatoid Arthritis
Motor Neuron Disease
Multifocal Motor Neuropathy
Diagnosis of Multifocal Motor Neuropathy
Therapy for Multifocal Motor Neuropathy
Electrophysiology of Multifocal Motor Neuropathy
Dr. William J. Triggs's Diagnosis
Diagnostic Discussion
Evolution and Response to Treatment
Anatomical Diagnosis
Source Information
From the McKnight Brain Institute and the Department of Neurology, University of Florida — both in Gainesville (W.J.T.); and the Department of Neurology, Massachusetts General Hospital and Harvard Medical School — both in Boston (D.C.).
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