Coronary artery disease remains an enormous clinical problem,affecting more than 15 million people in the United States alone,where it is the most common cause of death (accounting for onein three deaths).1 The prevalence of coronary heart diseaseis increasing at a particularly alarming rate in developingnations, which are ill equipped to shoulder the associated economicburden.2,3 The clinical need this represents underscores theimportance of understanding the causes of coronary disease andidentifying persons at risk.
Much progress has been made toward these goals. We now recognizemany clinical risk factors — such as hyperlipidemia and. . . [Full Text of this Article]
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From the Cardiovascular Division, Beth Israel Deaconess Medical Center, and the Harvard Stem Cell Institute — both in Boston.
This article (10.1056/NEJMe078121) was published at www.nejm.org on July 18, 2007.
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