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Clinical Implications of Basic Research
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Volume 357:502-503 August 2, 2007 Number 5
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Changing the Trajectory of Cognitive Decline?
Marilyn S. Albert, Ph.D.

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Delaying the onset of cognitive decline and reducing cognitive decline once it has begun have become increasingly important with the aging of the population. Age-related changes in cognitive functions such as memory occur even among healthy persons and have been seen in humans, nonhuman primates, and rodents. Moreover, several neurodegenerative disorders that cause cognitive decline are increasingly prevalent with age. The most common neurodegenerative disorder is Alzheimer's disease: about 5 million people in the United States have Alzheimer's disease, and current estimates indicate that about 16 million people will have the disease in 40 years. Delaying the onset of Alzheimer's . . . [Full Text of this Article]


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From the Department of Neurology, Johns Hopkins University School of Medicine, Baltimore.




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