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Previous Volume 357:506-507 August 2, 2007 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the study of rescue use of beclomethasone and albuterol in a single inhaler for mild asthma reported by Papi et al. (May 17 issue),¹ the morning peak expiratory flow rate (based on peak-flow diaries) was the primary end point, although there is enough reason to doubt its clinical relevance, its validity, and its physiological meaning in a disease that predominantly affects smaller airways. The peak expiratory flow rate reflects mainly central-airway mechanics² and is insensitive for the monitoring of peripheral-airway patency. Only because no Bonferroni correction was used, the morning peak expiratory flow rate — but . . . [Full Text of this Article]

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