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Previous Volume 357:682-690 August 16, 2007 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

A 52-year-old man who has had psoriasis since he was 20 years of age seeks further treatment. His psoriasis has varied in extent and severity over time, is not responsive to topical therapy, is worse in winter, and improves . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Department of Dermatology, Harvard Medical School, and Beth Israel Deaconess Medical Center — both in Boston.

Address reprint requests to Dr. Stern at the Department of Dermatology, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Ave., Boston, MA 02215, or at rstern@bidmc.harvard.edu.

This article has been cited by other articles:

• (2007). PUVA in the Age of Biologics. Journal Watch Dermatology 2007: 1-1 [Full Text]