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Case Records of the Massachusetts General Hospital
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Volume 358:1283-1291 March 20, 2008 Number 12
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Case 9-2008 — A 65-Year-Old Woman with a Nonhealing Ulcer of the Jaw
Thomas B. Dodson, D.M.D., M.P.H., Noopur S. Raje, M.D., Paul A. Caruso, M.D., and Andrew E. Rosenberg, M.D.

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Presentation of Case

Dr. Steven E. Smullin (Oral and Maxillofacial Surgery): A 65-year-old woman was seen in the oral surgery clinic of this hospital because of a nonhealing ulcer of the mandible.

Three years earlier, the patient had been referred to the oral and maxillofacial surgery clinic for evaluation and extraction of three teeth: the mandibular right cuspid and first bicuspid and the mandibular left second bicuspid. Dental extractions were performed on an outpatient basis with local anesthesia. The right mandibular teeth were extracted nonsurgically; the mandibular left second bicuspid required a surgical extraction with flap elevation and bone removal. At a postoperative . . . [Full Text of this Article]

Differential Diagnosis

Bisphosphonate-Related Osteonecrosis of the Jaw

Dr. Thomas B. Dodson's Diagnosis

Pathological Discussion

Discussion of Management

Use of Bisphosphonates in Multiple Myeloma

Management of Bisphosphonate-Related Osteonecrosis

Anatomical Diagnosis


Source Information

From the Departments of Oral and Maxillofacial Surgery (T.B.D.), Oncology (N.S.R.), Radiology (P.A.C.), and Pathology (A.E.R.), Massachusetts General Hospital; the Department of Radiology, Massachusetts Eye and Ear Infirmary (P.A.C.); the Department of Oral and Maxillofacial Surgery, Harvard School of Dental Medicine (T.B.D.); and the Departments of Oncology (N.S.R.), Radiology (P.A.C.), and Pathology (A.E.R.), Harvard Medical School.



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