The thoughtful clinician takes it to be self-evident that intensityof therapy should be proportional to risk of disease.1,2 Eversince Bigger coined the term "risk stratification" to characterizethis intuitive process,3 more than 3000 articles (accordingto a recent PubMed literature search) have been published onthe subject — at a rate that is doubling every 5 years.4Nearly 40% of these articles focus on cardiovascular medicine,where "risk stratification" has become something of a mantrafor rational, evidence-based clinical management.
Predicting who will have a cardiovascular event is indeed animportant clinical and societal goal. Currently, the United. . . [Full Text of this Article]
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From the Christiana Care Health System, Newark, DE (W.S.W.); and Cedars–Sinai Medical Center, Los Angeles (G.A.D.).
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Coronary Calcium and Events in Four Ethnic Groups
Payne P. W. Jr., Littmann L., Burtey S., Dussol B., Brunet P., Goyal S. K., Punnam S. R., Nasir K., Budoff M. J., Blumenthal R., Guerci A. D., Bild D. E., Kronmal R. A., Weintraub W. S., Diamond G. A.
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N Engl J Med 2008;
359:202-204, Jul 10, 2008.
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Payne, P. W. Jr., Littmann, L., Burtey, S., Dussol, B., Brunet, P., Goyal, S. K., Punnam, S. R., Nasir, K., Budoff, M. J., Blumenthal, R., Guerci, A. D., Bild, D. E., Kronmal, R. A., Weintraub, W. S., Diamond, G. A.
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