The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Correspondence
PreviousPrevious
Volume 358:1515-1517 April 3, 2008 Number 14
NextNext

Platelet-Activating Factor, PAF Acetylhydrolase, and Anaphylaxis

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-Related Article
by Vadas, P.
-PubMed Citation
To the Editor: Vadas et al. (Jan. 3 issue)1 report platelet-activating factor (PAF) and PAF acetylhydrolase levels in patients with anaphylaxis.1 But why did the investigators not measure tryptase levels and correlate findings with PAF levels? Tryptase levels are the standard for understanding mast-cell activation in anaphylaxis and can be measured within 1 to 2 hours after its onset. This is an important consideration when a patient is in unstable condition2 and is important with PAF's short half-life. On the basis of the authors' suggestion that blocking PAF may alter clinical outcomes, it is important to correlate PAF levels temporally . . . [Full Text of this Article]



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.