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Previous Volume 358:1750-1751 April 17, 2008 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: To preserve language function during glioma resection in or near language areas, Sanai and colleagues, including Berger (Jan. 3 issue),¹ advocate negative mapping through intraoperative cortical stimulation (negative cortical stimulation) instead of traditional positive cortical stimulation. Positive cortical stimulation identifies cortical sites associated with and sites not associated with motor, somatosensory, or language function, whereas negative cortical stimulation typically identifies only sites not associated with such function.

However, language requires not only cortical language sites but also subcortical (white-matter) language tracts to connect them. So preserving language function depends on preserving not only cortical language sites but . . . [Full Text of this Article]

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