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Previous Volume 358:1829-1836 April 24, 2008 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

A previously well, American-born 35-year-old man presents with a 5-day history of fever and progressive dyspnea and a 2-day history of jaundice. An evaluation 3 days before his presentation led to a diagnosis of a viral syndrome. The patient . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Department of Medicine, San Francisco General Hospital, University of California, San Francisco.

Address reprint requests to Dr. Rosenthal at Box 0811, University of California, San Francisco, San Francisco, CA 94143, or at prosenthal@medsfgh.ucsf.edu.

Related Letters:

Artesunate for Malaria
Arguin P. M., Weina P. J., Dougherty C. P., Gordi T., Itskowitz M. S., Kashyap A. S., Anand K. P., Kashyap S., Rosenthal P. J.
Extract | Full Text | PDF  
N Engl J Med 2008; 359:313-315, Jul 17, 2008. Correspondence

This article has been cited by other articles:

• Keiser, J., Gruyer, M.-S., Perrottet, N., Zanolari, B., Mercier, T., Decosterd, L. (2009). Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with Fasciola hepatica. J Antimicrob Chemother 63: 543-549 [Abstract] [Full Text]  
• Arguin, P. M., Weina, P. J., Dougherty, C. P., Gordi, T., Itskowitz, M. S., Kashyap, A. S., Anand, K. P., Kashyap, S., Rosenthal, P. J. (2008). Artesunate for malaria.. NEJM 359: 313-314 [Full Text]