The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Clinical Implications of Basic Research
PreviousPrevious
Volume 358:1860-1861 April 24, 2008 Number 17
NextNext

Mast Cells and Pancreatic Cancer
Theoharis C. Theoharides, Ph.D., M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-PubMed Citation
Pancreatic ductal adenocarcinoma is probably the most lethal cancer, with a median survival of less than 6 months and a 5-year survival rate of less than 5%. The cause of pancreatic ductal adenocarcinoma is unknown, and this type of cancer resists all currently available treatments. Increasing evidence indicates that inflammation around tumors, including infiltration by mast cells, facilitates cancer growth, especially that of pancreatic ductal adenocarcinoma.1

Mast cells are derived from a unique bone marrow precursor, and they mature in the tissues. They are commonly known for their role in allergic and anaphylactic reactions, during which they secrete numerous vasoactive, . . . [Full Text of this Article]


Source Information

From the Tufts University School of Medicine and Tufts Medical Center — both in Boston.



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.